The former Hindu shrine of Prang Sam Yot (Three Peak Towers) is Lop Buri's most famous landmark. The 3 towers were originally based on Khmer art and architecture, but local artisans gave it the Lop Buri touch by adding Buddha images and modifying with several other variations. The shrine was converted to a Buddhist temple during King Narai's reign.

The Statue of King Narai the Great stands near the provincial capital's entrance to commemorate the great Ayutthayan monarch who helped Lop Buri prosper. King Narai is remembered for fostering close diplomatic ties with European powers and introducing western technology, such as terra cotta pipes to supply drinking water.

The square-shaped Wat Phra Si Rattana Mahathat complex encloses ruins from two distinct eras. At the center is the finely detailed 12th-century stucco Khmer prang. Scattered around the complex are chedis built in the Ayutthaya and Sukhothai-styles and a wiharn (hall) commissioned by King Narai.

The Vichayen House was built as a residence for the first French ambassador to Thailand during the reign of Louis XIV. Later it was inhabited by the King's favorite minister, the Greek Constantine Phaulkon, who encouraged King Narai to forge close ties with the Europeans, predominantly with the French. Scattered around the compound are other ruined buildings that served as residences for other mission members, water tanks, fountains, and a Roman Catholic chapel.

King Narai's Ratchaniwet Palace was constructed during mid-1600s and was abandoned after his death. The palace combined both Thai and western-style architecture, indicating the European's influence during that period. Later on, King Mongkut, Rama IV restored parts of the palace, including the majestic Chanthara Phisan Pavilion, originally the royal residence of King Narai built purely in Thai-style.

The three-storied, colonial-styled Phiman Mongkut Pavilion within King Narai's Palace served as King Mongkut's (Rama IV) residence during the palace renovations. Connected to it are three other two-storied pavilions. Nowadays, the buildings have been converted into the Narai National Museum which houses a superb collection of Lop Buri Buddha images and earlier kingdom's arts.

The Kraison Siharat Hall is located on an island in the dried up Tale (lake) Chupson that formerly supplied drinking water to the city of Lop Buri. King Narai built the place to be used by him and Louis XIV's envoys to witness a lunar eclipse on December 11, 1685.

Wat San Paolo originally served as a Jesuit church during King Narai's reign.

Situated at the foot of Sanam Daeng (Red Field) Mountain is Wat Khao Wongkot that has a large bat cave. The featured attraction occurs daily around 6 p.m. when a massive amount of bats leave the cave, taking 2 hours to fully empty out the cave. Bat droppings can be purchased at the temple.

The nation's largest Sunflower Field is located some 45 km from town. Tourists swarm the fields during the months of November to January when the sunflowers are in full bloom.